Perspectives

How does this study impact clinical practice?

• Primary care clinicians, neurologists, and headache specialists treating patients with migraine should take into account that female patients have an elevated risk of migraine from day -2 to day +3 of the menstrual cycle in their treatment plan.
• Between- and within- woman variation of migraine is critical for progressing clinical theory and practice.
• Modern developments in electronic data collection and statistical analysis can be leveraged to better bridge the gap between headache research and clinical practice.