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Background

What do we already know about this topic?

  • Diagnosis of menstrually-related migraine is based upon a 5-day perimenstrual window (2 days prior to the start of menstruation and the first 3 days of bleeding).1
  • The odds of migraine increase around the perimenstrual window at the population level.2,3
  • Menstrual migraine research has overlooked between- and within-woman variation, which is critical for progressing clinical theory and practice.

How was this study conducted?

  • A longitudinal study utilizing data from N1-Headache® digital platform on daily migraine and menstruation status from actively menstruating adult women with migraine over 90 days (N=203).
  • Variables of primary interest were migraine day, and menstrual status (inside or outside the 5-day perimenstrual window).
  • Data were analysed using three-level binary multilevel models.