Perspectives

How does this study impact clinical practice?

• CGRP-antagonists are efficacious and well-tolerated in real-world clinical practice but patients may experience more common side-effects, such as constipation, than reported in clinical trials.
• Further data will be collected on the long-term use of CGRP-antagonists in the real-world to provide additional insight and monitor changes in treatment response over time and long-term side effects.