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Headache & COVID-19 challenges and insight

Key messages

  • Headache is a key symptom that is indicative of the different clinical evolution of COVID-19.
  • Headache may manifest during the asymptomatic or symptomatic period of the disease and have migraine-like or tension-type features.
  • Patients who present with headache experience a typically shorter duration of disease and those with a headache plus anosmia are hospitalised for a shorter duration.
  • A subgroup of patients suffers from headache following COVID-19 symptom resolution.
  • Understanding the pathophysiology of headache associated with COVID-19 may add to the current understanding of migraine and headache in a wider context.