Hematology
| Primary ITP
Hematology
Primary ITP
Prolonged response after TPO-RA discontinuation in primary ITP: results of a prospective multicenter study
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Source:
Blood. 2023;141(23):2867-77.
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Published on Medfyle:
June 2023
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4
min
In this medfyle
TPO-RAs are associated with immune modulation. However, whether these agents can induce sustained improvement in the platelet count, even after discontinuing TPO-RA therapy, was unknown until now. High rates of sustained platelet response were achieved following discontinuation of TPO-RA therapy in adult patients with persistent or chronic ITP and a documented CR (platelet count >100 × 109/L). Progressive tapering and discontinuation of TPO-RAs for patients with chronic ITP who achieve stable CR on treatment is a suitable treatment strategy.
