Efficacy of celecoxib (DFN-15) in the acute treatment of episodic migraine

Key messages

• Celecoxib shows efficacy as an acute treatment for episodic migraine through inhibiting prostaglandin synthesis.
• Treatment with celecoxib, as oral solution DFN-15, resulted in significant pain reduction and migraine symptoms compared with placebo in adults.
• DFN-15 presents no serious treatment-emergent adverse events (TEAEs) or remarkable findings in safety assessments.