| Integrated Physiology/Obesity
Integrated Physiology/Obesity

New Insights from the Restoring Insulin Secretion (RISE) Study—Differences between Adults and Youth with Prediabetes and Type 2 Diabetes

book_2 Source: ADA 2020 - Oral session
calendar_today Published on Medfyle: June 2020
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In this medfyle

Expert commentary by Dana M. Dabelea, MD, PhD

This Medfyle was published more than two years ago. More recent Medfyle on this topic may now be available.

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This is a highlights summary of an oral session given at the ADA 2020 - 80th Scientific Sessions and presented by:

Sharon Edelstein, ScM
Dept. of Epidemiology & Biostatistics, George Washington University, Washington, DC, USA

Thomas A. Buchanan, MD
Dept. of Physiology and Biophysics and Department of Medicine, Keck School of Medicine of USC, Los Angeles, CA, USA

Kristina Utzschneider, MD
Division of Metabolism, Endocrinology and Nutrition, University of Washington, Seattle, WA, USA

Kristen J. Nadeau, MD, MS
Section of Pediatric Endocrinology, Dept. of Pediatrics, University of Colorado - School of Medicine, Aurora, CO, USA

The content is produced by Infomedica, the official reporting partner of ADA 2020 Virtual Meeting. The summary text was drafted by Patrick Moore, PhD, and reviewed by Marco Gallo, MD, an independent external expert, and approved by Dana M. Dabelea, MD, PhD, the scientific editor of the program.

The presenting authors of the original session had no part in the creation of this conference highlights summary.

In addition, an expert commentary on the topic has been provided by:

Dana M. Dabelea, MD, PhD
University of Colorado
Director of the LEAD Center and Conrad M. Riley Endowed Professor
Denver, CO, USA

About the Expert
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Dana M. Dabelea, MD, PhD
University of Colorado
Director of the LEAD Center and Conrad M. Riley Endowed Professor
Denver, CO, USA

Dr. Dabelea is a Professor of Epidemiology and Pediatrics and the Director of the Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center at the University of Colorado Anschutz Medical Campus (AMC).

Her main research interest is understanding how early life behaviors, environmental exposures and other risk factors operating during fetal or early post-natal life, influence the development of obesity, diabetes  and cardiovascular outcomes throughout the lifecourse (developmental origins of health and disease). Her experience includes epidemiological studies with community-based and clinic-based sampling, longitudinal follow-up, and extensive sample collection and storage.

As the Director of the LEAD Center and lead investigator on over $18 million NIH and CDC grants, she oversees large, longitudinal, cohort studies spanning the entire lifecourse, from pregnancy through old age. Among others, she serves as national Co-Chair of the Steering Committee for the multi-center SEARCH for Diabetes in Youth Study. SEARCH is a landmark US population-based study conducting both surveillance and observational research in the field of pediatric type 1 and type 2 diabetes. Dr. Dabelea is also part of the Diabetes Prevention Program Outcomes Study (DPPOS), another landmark US diabetes study in older adults, which has provided the evidence base for diabetes prevention efforts, and is now studying diabetes-and aging-related outcomes and comorbidities.

Finally, Dr. Dabelea is also Principal Investigator of Healthy Start, a Colorado pre-birth cohort study following over 1400 mother –child dyads from before birth through childhood and adolescence, to understand the developmental origins of several chronic pediatric diseases. With Healthy Start, Dr. Dabelea leads a multi-disciplinary team of investigators, as part of the NIH-assembled ECHO consortium (Environmental influences on Childhood Health Outcomes). These studies, several ancillary studies supported by these cohorts, as well as other studies conducted by LEAD investigators under Dr. Dabelea’s direction, provide an exceptionally rich resource for training and mentoring students, junior faculty, residents and fellows in clinical diabetes research, lifecourse research, maternal and child health research, and chronic disease epidemiology.