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Perspectives

How does this study impact clinical practice?

  • The subcortical regions such as the hypothalamus, thalmus and basal ganglia are involved during the early phases of migraine.
  • Functional reorganisation of the brain networks occurs between the subcortical and cortical areas which fluctuate during different phases of a migraine attack and lead to corresponding symptoms.
  • The study furthers our understanding of the abnormal sensory processing and integration that occurs during a migraine, and the functional correlation with clinical symptoms displayed during each phase.
  • This knowledge could lead to the development of disease and treatment biomarkers in the future to improving patient outcomes and prognosis.