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Safety and pharmacokinetics of atogepant in migraine

Key messages

  • Once-daily oral atogepant 170 mg for the prevention of migraine was safe and generally well-tolerated over a 28-day period.
  • Atogepant is rapidly absorbed and has an estimated half-life of ~10 hours.
  • The potential risk of liver injury from multiple doses of atogepant appears to be relatively low.